AUGMENTATION OF PRESSOR RESPONSE TO EXOGENOUS RENIN IN RATS WITH ACUTE MERCURIC CHLORIDE INTOXICATION : FAILURE TO DEMONSTRATE RENIN ACTIVATING PRINCIPLE (S) IN PLASMA
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چکیده
منابع مشابه
The prolonged pressor response to renin in the nephrectomized rat.
Angiotension I dose-response curves and renin clearances were studied in nephrectomized and paired sham-nephrectomized control rats under pentobarbital anesthesia. Both threshold and slope of the angiotensin dose-response curves were decreased 22 hours after nephrectomy. In addition, the ratio of renin clearance (determined during renin infusions) in the 22-hour-nephrectomized rat to that in pa...
متن کاملChanges in blood pressure in relation to vascular and plasma renin after renin injection in rats
1. To assess the relative importance of vascular as opposed to plasma renin, groups of conscious rats received a single intravenous injection of partially purified rat renin 18 h after bilateral nephrectomy. Blood pressure was monitored continuously and plasma and aortic renin concentrations were determined at 1, 3, 6 or 9 h after injection. In separate groups of rats the effect of the competit...
متن کاملClinical Science and Molecular Medicine (1974) 47,7948. THE RENIN-ANGIOTENSIN SYSTEM I N ACUTE RENAL FAILURE I N RATS
1. Serial changes in plasma renin activity and plasma angiotensin levels were followed in rats during acute renal failure induced by mercuric chloride or glycerol. 2. During mercuric chloride-induced acute renal failure there were transitory large increases in plasma renin and angiotensin. In contrast, rats with acute renal failure produced by glycerol had a reduction in plasma renin and angiot...
متن کاملThe pressor response to angiotensin II in patients with low renin essential hypertension.
The etiology of low renin essential hypertension (LREH) has not been established with certainty, but mineralocorticoid excess has been implicated frequently in its pathogenesis. The finding of several investigators of a normal exchangeable sodium space and extracellular fluid volume, however, does not support this hypothesis. To evaluate the possible role of sodium and water retention in LREH, ...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1973
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.37.1069